1600 AD

During the Italian Renaissance, lead powder and paint was used to lighten the face, which was very damaging to the wearer. Aqua Toffana was a popular face powder made from arsenic, belladonna and lead and named for its creator, Signora Toffana. Signora Toffana instructed her rich clientele to apply the makeup only when their husbands were around. Signora Toffana was finally accused of over 600 deaths [mostly husbands of clients] linked to her powder and liquid poisonous beauty concoctions.

2matthew waitesmith